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Does Remdesivir Save Lives?

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The data is in. A medical website ran this (1) headline recently;    

Remdesivir Finally Shows Mortality Benefit in Hospitalized COVID Patients

Finally? After 3 years of controversy (2), the prescription drug, Remdesivir FINALLY was shown to lower the death rate of COVID?  Did it actually show that? Wasn’t Remdesivir the only drug that doctors were allowed to treat COVID with because of its published success of saving lives?  It seems that any drug that competed with it, even drugs that have been on the market for decades, were dismissed as ineffective. The stats they published in this paper were equally confusing and candidly I don’t think I would have even published them.  Medical websites are rarely read by we the people. They are mostly for doctors to read, or not.

“Of the patients on ventilation, including high-flow oxygen, 30% of remdesivir-treated patients died versus 28.5% of those not treated with remdesivir (aOR 1.10, 95% CI 0.88-1.38).”  Doesn’t that sound like your chances of living rose by a tick (versus doing nothing) if you DID NOT take Remdesivir? Someone please correct me if I am wrong, but that is like saying, “Doctor, if your COVID patients are not on a respirator, they have a very slightly better chance (than doing nothing) if you prescribe Remdesivir for them. But if they are on a respirator, prescribing Remdesivir actually very slightly increases their risk of dying.”  And doesn’t Remdesivir cost $4,000?  What a bizarre way of patting oneself on the back!

Please be careful whom you trust these days.  There are no shortages of financially gluttonous institutions that can spin media releases into anything they want.

Research and References

1. MedPageToday: Remdesivir Finally Shows Mortality Benefit in Hospitalized COVID Patients | MedPage Today

2. Science.org: The ‘very, very bad look’ of remdesivir, the first FDA-approved COVID-19 drug | Science | AAAS

 

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