Mycotoxin Exposure and Early Puberty

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Many Fusarium molds can produce zearalenone mycotoxins on grains, flours and other foodstuffs.   Moldy corn can be especially rich in zearalenone.  Zearalenone can mimic the hormone estrogen and have estrogenic effects on the body.  Heavy mold exposure in grains can cause infertility and reproductive problems in cattle and swineny Fusarium molds can produce zearalenone mycotoxins on grains, flours and other foodstuffs.   

Moldy corn can be especially rich in zearalenone.  Zearalenone can mimic the hormone estrogen and have estrogenic effects on the body.  Heavy mold exposure in grains can cause infertility and reproductive problems in cattle and swine.

Exposure to zearalenone has been associated with higher rates of precocious (early) puberty in girls.  An Italian study measured blood levels of the mycotoxin zearalenone in girls with precocious puberty (patients had breast development and/or development of high estrogen levels before age 8). Six of the 32 girls with precocious puberty had high blood levels of zearalenone (average level of 934 picograms per milliliter of blood serum), while 0 of 32 control girls without precocious puberty had blood levels of zearalenone exceeding 25 picograms per milliliter of blood serum.  .Other studies have linked early female puberty with eating moldy corn and other grains.

Source

–          Francesco Massart et al. High growth rate of girls with precocious puberty exposed to estrogenic mycotoxins.  Journal of Pediatrics May 2008;152:690-5.

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