Invasive Candida A Menace To Low Birth Weight Babies.

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Candida is a yeast (fungus) that frequently grows in the skin, digestive tract and urinary/ reproductive tracts of humans. Candida can cause life-threatening infections- especially in patients who are have compromised immune systems such as cancer patients, patients on immunosuppressive drugs, HIV patients and very premature babies.     

Lorena-Botero-Calderon et al. Advances in the treatment of invasive neonatal candidiasis. Expert Opinion Pharmacotherapy 2015; 16:1-14.

Candida is responsible for 10% of hospital acquired infections in 10% of all very low birth weight (<1,500 grams) babies. Death rates from neonatal Candida infections are very high at 20-30% and 59-73% of survivors of neonatal Candida infections have long-term neurodevelopmental impairment. Most cases of neonatal Candida are caused by 2 species- C. albicans and C. parapilosis. C, glabrata, and C. krusei can also occasionally cause infections.

Proper handwashing and sufficient nutrition can reduce the risk of neonatal Candida infections. The best drugs for treating neonatal Candidiasis are believed to be amphote

 

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