|An excellent review of the effects of probiotics and Candida growth is provided in a recent issue in Clinical and Infectious Diseases. This review covered peer reviewed papers published from 2000 to 2015.|
A number of human, animal, and laboratory studies have examined the effects of probiotic on Candida growth and infections. Probiotics inhibited Candida growth and virulence in all 12 of 12 in vitro (cell cultures) studies. In human clinical studies, use of probiotic bacteria supplements were reported to significantly inhibit Candida growth and/or significantly improve clinical outcomes (such as less infection, lower infection rates, shorter hospitalization, or reduced symptoms of vulvovaginal candidiasis) in 5 out of 7 studies involving the mouth/oral cavity, 4 out of 5 studies involving the urogenital tract, and in all 7 out of 7 studies involving the gastrointestinal tract (Matsubara, Bandara et al. 2016).
Mixtures of probiotic strains may be more effective that single strains. A review of 16 published studies examining the health effects of probiotic supplements reported that 12 of these studies reported that mixtures of probiotics gave significantly better response than single probiotics- while a similar clinical response between multiple and single probiotics was reported in the 4 other studies (Chapman, Gibson et al. 2011) In the future, oral and topical Candida treatment may be increasingly used to prevent and treat Candida related health problems.
References / Sources
Mezzasalma, V., et al. (2016). “A Randomized, Double-Blind, Placebo-Controlled Trial: The Efficacy of Multispecies Probiotic Supplementation in Alleviating Symptoms of Irritable Bowel Syndrome Associated with Constipation.” Biomed Res Int 2016: 4740907.
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