|Crohn’s disease is a serious inflammatory bowel disease affects about 1 in 300 people and can flare up in any part of the GI tract. Crohn’s can cause many serious problems including abdominal pain, diarrhea, fever, weight loss, malnutrition, and fatigue.|
Another study of 9 families in France and Belgium reported that stool specimens of Crohn’s disease patients had significantly higher levels of the fungi Candida tropicalis and the bacteria Escherichia coli and Serratia marcescens as compared to the stools of cohabiting first degree relatives without Crohn’s (Hoarau, Mukherjee et al. 2016). Related studies have reported that Candida tropicalis and other Candida species along with the bacteria Escherichia coli and Serratia marcescens frequently form multiple species biofilms in the intestine’s of Crohn’s patients. It is hypothesized that the combination of these 3 organisms may be especially inflammatory and toxic to the intestines.
References / Sources
Shen, J., et al. (2014). “Effect of probiotics on inducing remission and maintaining therapy in ulcerative colitis, Crohn’s disease, and pouchitis: meta-analysis of randomized controlled trials.” Inflamm Bowel Dis 20(1): 21-35.
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