|Candida is a common fungus (yeast or mold) which frequently grows on human skin and in the digestive, urinary, and reproductive tracts. Candida species in the gut produce allergens, alcohols and toxins which can have adverse health effects.|
A case report of the first seven cases in the USA between 2013 and 2016 was made. All cases were treated with strong antifungal drugs including echinocandins, but four patients still died 2. Another study reported a death rate of 59% for 54 cases of invasive Candida auris in India, Pakistan, South Africa and Venezuela
3 . Antibiotic resistance was very high in this series, with 93% Candida auris isolates being resistant to fluconazole, 35% to amphotericin B, and 7% to echinocandins. Forty-one percent of the Candida auris strains were resistant to 2 different antifungal drugs and 4% were resistant to all 3 classes 3. In is likely that Candida auris infections will increase worldwide. Prompt diagnosis and treatment with multiple fungal drugs of Candida auris is essential to control the epidemic.
References / Sources
2. Vallabhaneni S, Kallen A, Tsay S, et al. Investigation of the First Seven Reported Cases of Candida auris, a Globally Emerging Invasive, Multidrug-Resistant Fungus-United States, May 2013-August 2016. Am J Transplant 2017;17(1):296-99. 3.Lockhart SR, Etienne KA, Vallabhaneni S, et al. Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses. Clin Infect Dis 2017;64(2):134-40.
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